Aspirin Research Acetylsalicylic Acid Bleeding

Low-dose Aspirin Linked To Bleeding In The Skull, New Report Says

Taking low-dose aspirin to prevent heart disease and stroke is associated with an increased risk of bleeding in the skull in people without a history of those conditions, according to a new report.


“Taking low-dose aspirin to prevent heart disease and stroke is associated with an increased risk of bleeding in the skull in people without a history of those conditions, according to a new report.”

Researchers analyzed data from 13 previous studies in which over 130,000 people ages 42 to 74, who didn't have a history of heart disease or stroke, were given either low-dose aspirin or a placebo for the prevention of these conditions.

An aspirin is typically defined as low-dose if it is between 75 and 100 milligrams, but most over-the-counter pills are around 81 milligrams.

People who took the placebo had a 0.46% risk of having a head bleed during the combined trial periods. For those who took low-dose aspirin, the risk was 0.63%, the equivalent of an additional 2 out of every 1,000 people developing a bleed, according to the study, published Monday in the journal JAMA Neurology.

People from Asian backgrounds and those with a body mass index under 25 had the highest risk.

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